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About

Proteomics-Metabolomics

Overview of Services

 

The Biological Mass Spectrometry Center at Stony Brook was established in the Health Sciences Center at the University at Stony Brook in 1985.
The Proteomics Core Facility at Stony Brook University School of Medicine supports basic and clinical research programs by performing mass spectrometry-based analyses of proteins and peptides. 
The facility offers state-of-the-art instrumentation and software for qualitative (e.g. protein identification), quantitative proteomics analysis (e.g. relative quantification), and post-translational modification (PTM) analysis. 
The Proteomics Center also supports small molecule and metabolic analysis. 
We offer services of sample preparation, LC-MS/MS analysis, statistical analysis, and data mining for large-scale proteomic projects. 
Center directors are available to provide expert consultation on experimental approaches and design.

 

Experiments

 

  • Protein identification from cells, tissues, FFPE slides, immunoprecipitations, CLICK, BioID/TurboID
  • Global protein expression profiling and quantitation (label fee quant, SILAC, iTRAQ/TMT) using C18 or SCX-C18 chromatography
  • Identification of post-translational modification (phospho, acetyl, methyl, ubi, etc.)
  • Meausurement of small molecules, metabolites (TCA, glycolytic, SCFA, LCFA, drug cpds, etc)
  • Pharmacokinetics


 Instrumentation
 

Thermo Q-Exactive HF orbital trap, with nano uHPLC

Sciex 5600+ QqTOF, with with nano uHPLC and with normal flow HPLC

(2) Agilent 6490 QqQ with uHPLC

Bruker RapiFlex MALDI

Agilent GC-MS

Olink PEA instrument

 

 

 

Location and Hours of Operation

 

Hours:

8:00am - 5:00pm Monday thru Friday

 

Location:

Proteomics Center
Basic Science Tower
T-9, Rm 167
SUNY
Stony Brook NY 11794-8691

 

Links and Resources

 

 

 

Contacts

Name Role Phone Email Location
Dr. Guangtao Li
Senior Scientist
 
(631) 444-3789
 
guangtao.li@stonybrook.edu
 
BST 9-167
 
Dr. Daniel Canals
Co-Director
 
(631) 216-2903
 
daniel.canals@stronybrookmedicine.edu
 
BST 9-167
 
Dr. John Haley
Director
 
(631) 444-3097
 
john.haley@stonybrookmedicine.edu
 
BST 9-168
 
Dr. Bahman Khavati
Scientist
 
(631) 444-2598
 
Bahman.Khalvatifahlyani@stonybrook.edu
 
BST-9-167
 
Dr Mahsa Lotfi
Senior Scientist
 
(631) 444-2598
 
Mahsa.LotfiMarchoubeh@stonybrookmedicine.edu
 
BST-9-167
 

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